PhD Completion Seminar

11:00 am

Wednesday, 15th Apr 2015

V206, Mathematics Building

Mr Meksianis Ndii

(School of Mathematical and Physical Sciences, The University of Newcastle)

Mathematical model of dengue transmission dynamics in the presence of Wolbachia

Dengue is caused by four different serotypes, where individuals infected by one of the serotypes obtain lifelong immunity to that serotype but not for the other serotypes. Individuals with secondary infections may attract the more dangerous form of dengue, called dengue hemorrhagic fever (DHF), because of higher viral load. Because of unsustainability of traditional measures, the use of the bacterium Wolbachia has been proposed as an alternative strategy against dengue fever. However, little research has been conducted to study the effectiveness of this intervention in the field. Understanding the effectiveness of this intervention is of importance before it is widely implemented in the real-world. In this talk, I will explain the effectiveness of this intervention and present mathematical models that I have developed to study the effectiveness of this intervention and how these models are different to the existing one. I will also present the effects of the presence of multiple strains of dengue on dengue transmission dynamics.

Supervisors: David Allingham, Roslyn Hickson (IBM), Kathryn Glass (ANU), Irene Hudson